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[Timothykacle]

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First time trying Yesglasses and absolutely buying more. I was looking for this style specifically and couldn't find it anywhere. Gave them a try and love them. I was careful to check the sizing before I purchased but they make it very clear so it all worked out. Frames seam to be good quality and the lens are crystal clear. I've only had them a couple of days but so far I'm super impressed. Going to be making at least two more purchases.
The glasses are of good quality and phenomenally priced. The progressive lenses are produced perfectly given my PD. The Try on option works exceptionally as it sizes the glasses per your PD. I also had a good experience with their customer services on changing some glasses that did not work in the past. Don't spend ridiculous amounts on glasses elsewhere as they have created a syndicate to fix high prices for what is really plastic. I feel Yesglasses should go lower than it already is.
I've had difficulty finding acetate frames of this style that aren't $250+ without prescription lenses, or are a bit small. These fit great, also come in several colours I like, and I can get brown tint lenses instead of gray.
This was the first pair of Yesglasses I tried. They were CUTE, but much too big. I thought that my head would be a medium size, but these were definitely still too large. They were also somewhat heavy and fell down my face frequently. I was able to contact support and receive a replacement which went very smoothly.
This was my first time buying from Yesglasses so I was skeptical BUT pleasantly surprised! Shipping was quick and the Wall-e is very high quality. They fit perfectly albeit I measured them 134mm from screw to screw so keep that in mind. Regardless, I will (and already have) place another order soon!
My rate is 4 because there is no option to choose the size of the frame. It looks much bigger than I expected. But my expectations are my own responsibility.Plus the frame plastic shines very bright. It doesn't feel like something fancy like Moscot or Montblanc. However for that price it's a really good bargain!
The quality is very good, the only thing I kind of not like a lot is how the grey polarized sometimes looks green, I get that they're polarized but maybe finding another provider for better polarized would be good. The frames are amazing.
Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit The Creative Commons Public Domain Dedication waiver ( ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
DT early diastolic mitral flow deceleration time, D/S pulmonary venous flow (S peak systolic wave velocity and D peak diastolic wave velocity), E/A peak velocity during early filing(E), late filling from atrial contraction (A), IVST interventricular septal thickness, LVEF left ventricular ejection fraction, LVEDD left ventricular end diastolic diameter, PASP pulmonary arterial systolic pressure, LVPWT left ventricular posterior wall thickness
ALT alanine transaminase, AST aspartate aminotransferase, α-HBDH α-hydroxybutyrate dehydrogenase, BUN blood urea nitrogen, BMI body mass index, CR creatinine, DBP diastolic blood pressure, HCT hematocrit, HR heart rate, HCY homocysteine, HDL-C high-density lipoprotein cholesterol, LDH lactate dehydrogenase, LDL-C low-density lipoprotein cholesterol, RBC red blood cell, SBP systolic blood pressure, TC total cholesterol, UA uric acid, WHR waist hip ratio, WBC white blood cell
The authors would like to thank Dr. Qiong-yin Wang for her critical English editing. Also, we would like to thank the funding of this research: National Natural Science Foundation of China (NSFC 81960086).
All authors fulfill the criteria for authorship. JY conceived and designed the research. JSC, PY acquired the data. JSC, CEL, NYL, TG drafted the manuscript and made critical revision of the manuscript for key intellectual content. All authors read and approved the final manuscript.
This study was supported by the National Natural Science Foundation of China (NSFC 81960086). The funding bodies did not play any roles in the design of the study and collection, analysis, and interpretation of data and in writing the manuscript.
Since some patients did not allow us to publish their medical records, datasets generated and/or analyzed in the current study are not publicly available, but can be obtained from the correspondence author on reasonable request.
Speckle tracking echocardiography has been widely used in clinical practice. However, due to the complexity of the left atrial geometry, traditional left ventricular measurement software cannot effectively evaluate left atrial function [5]. Real-time three-dimensional echocardiography and left atrial automatic strain technology (Autostrain LA) can accurately and quantitatively evaluate LA function [6,7,8]. This article aims to evaluate the corresponding strain and its derived parameters of left atrium in patients with CHD through Autostrain LA technology and explore their correlation with left ventricular diastolic function.
AutoStrain LA image from four-chamber apical view. Setting the starting point (Reference PerA) of strain analysis at the beginning of the p wave on the ECG allowed us to define first negative peak, first positive peak and the difference of these peaks which corresponded to atrial contractile strain (LASct), conduit strain (LAScd) and reservoir strain (LASr)
The final stage of CHD usually progresses to heart failure, and the initial stage of the disease development is often characterized by left ventricular diastolic dysfunction. Reduced left ventricular diastolic function is more sensitive to myocardial ischemia and appears earlier than reduced left ventricular systolic function. Therefore, early identification of LVDD in CHD patients is of great significance to improve clinical prognosis and reduce mortality.
In this study, grouping was conducted according to the guidelines [3]. The results indicated that when LVDD was definitively diagnosed based on the guidelines, the left ventricular diastolic function had already decreased, accompanied by structural changes in the left atrium. However, previous studies [9,10,11,12] have confirmed that functional changes in the left atrium precede structural changes. Functional impairment is a better indicator of the degree of pathological changes and remodeling in the left atrium compared to volumetric changes [13]. Therefore, in patients with uncertain diastolic function, there may be no significant changes in conventional structural parameters, while the left atrial function has already undergone alterations.
Different from ventricular muscle, atrial muscle is thinner and consists of two layers of muscle structure: the superficial layer and the deep layer. The superficial layer runs horizontally and surrounds the left and right atria, while the deep layer is divided into circular muscle and longitudinal muscle. The complex arrangement of left atrial muscle fibers determines its complex motion patterns [23]. Autostrain LA technology is an extension of two-dimensional speckle tracking imaging technology. Unlike previous studies that used left ventricular speckle tracking software to measure and analyze left atrial strain, Autostrain LA achieves time-resolved quantitative dynamic assessment of left atrial myocardial deformation by automatically tracking the motion trajectory of echo speckles that move synchronously with the left atrial myocardium, without being affected by sound beam angle or cardiac preload and afterload [24, 25]. Some studies have pointed out that the specialized left atrial strain analysis software significantly improves the intra-observer and inter-observer reproducibility [26].
There are some limitations in this study: LVDD was not graded to compare the correlation between each index and diastolic function in different grades of LVDD; Only LASr, LAScd, and LASI have been shown to evaluate LV diastolic dysfunction, but their diagnostic efficacy will be further improved in future studies; The lack of further exploration into the correlation between coronary artery lesion sites and parameters like LASI, as well as the relatively small number of cases.
LA function in CHD patients is closely related to LV diastolic function. LASr, LAScd, and LASI have a certain reference value for evaluating LV diastolic function in patients when the guidelines cannot make a determination, providing imaging evidence for early clinical intervention measures, improving prognosis, and reducing mortality rates. cc7c31b456 winber
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